We all know that the main attention in the sportsbook will be the Pacquiao Cotto odds, so here’s a breakdown of that mega event along with a pick.

Manny Pacquiao is money. On Saturday, November 14th, he will again be money in the bank as he takes on Miguel Cotto. While Cotto is the bigger fighter, he doesn’t have the type of experience that Pacquiao has – this will be his first big fight in Las Vegas. For Pacquiao, he has the best trainer in his corner and they are going to break down Cotto rather easily. If Cotto struggled against Joshua Clottey, he is going to get knocked out by Pacquiao rather easily.

Internet Betting pick: Pacquiao via 6th-round knockout

Most people are getting excited in the racebook for the Breeders Cup Stakes but we’ve got events to bet on before then. Let’s take a look at the Thursday night college football action.

College Football Matchup: North Carolina Tar Heels @ Virginia Tech Hokies

Online Betting odds: Virginia Tech -17.5

The North Carolina Tar Heels have been an absolute nightmare this year. They were supposed to be a decent contender in the ACC but instead, they are 4-3 and have yet to win a conference game. The Tar Heels hit rock bottom last week with a loss to Florida State where they blew an 18-point third quarter lead. The Hokies are rested off of their bye and will roll.

NFL picks: Hokies -16.5

While most people have their eye on the district attorney and what they plan to do with the potential betting ring involving the tennis scandal and No. 6 seed Caroline Wozniacki, our main focus is still the daily betting. Let’s take a look through the BetOnline.com book and make some picks for the weekend:

NFL Betting: New England Patriots @ Tampa Bay Buccaneers

The Tampa Bay Buccaneers get to lose a home game this week as the NFL scheduled this contest for London, England. On top of that, they are 0-6 and desperate to get a win, but they have to face the New England Patriots. Good luck. By the way, the Bucs defense gave up over 250 rushing yards last week and they lead the league in passing plays allowed of 40 yards or longer. Enter Tom Brady and Randy Moss as the Pats surpass 50 points for a second straight week.

NFL picks: Patriots -14.5

The College Football Weekend should be a good one with plenty of key matchups but we get a good one on Thursday night as well with a Top 25 matchup.

College Football Odds: Cincinnati Bearcats @ South Florida Bulls

Sportsbook odds: Bulls -3

To be quite frank, the Bulls don’t deserve to be favored in this game. Both teams are ranked, both teams are unbeaten and both teams haven’t had to play anyone too difficult on their schedule but Cincy has been the better team. The Bearcats have the two-time Big East Coach of the Year on their side and they have the better track record. There is no reason to lay points with USF.

Sports Picks: Cincy +3

If you’re looking to bet on horses, the Breeders Cup is coming up. But our focus is more on the big UFC event upcoming.

UFC 104: Lyoto Machida vs Mauricio Rua

Odds: Machida -410

People making their sports picks aren’t going to be siding with Rua in this contest and it’s pretty easy to understand why. Rua looked really sluggish against Mark Coleman earlier in the year but then hammered an over the hill Chuck Liddell. But Lyoto Machida is a champ and he will be for a long time. His unorthodox karate style is a big problem for anyone to get at and if you can’t hit him, you aren’t going to win. Machida is going to pummel Rua rather easily in this fight.

Sportsbook pick: Machida -410

If you are one of those guys that bet horses, don’t worry about it until the Breeders Cup next month. Let’s take a look at some hockey futures:

NHL Preview: Ottawa Senators

Sportsbook Regular Season Point Total: 84.5

The Ottawa Senators are a very underrated team this year. True, they aren’t the Eastern Conference powerhouse they once were but they could genuinely be a very dangerous playoff team in the East. The Senators upgraded their goaltending with the acquisition of Pascal Leclaire and they have more depth after trading away Dany Heatley. Also, they should have more chemistry.

The over/under for the Senators in the sportsbook is at 84.5. Look for them to go over that number rather easily. They had 83 points last year in a sluggish year.

Sports betting system pick: Senators over 84.5

A lot of racebook bettors are interested in what’s going on with the New England Patriots but not to worry, they will bounce back.

NFL Picks: Atlanta Falcons @ New England Patriots

NFL betting line: Patriots -4

Sure, the New England Patriots have looked sluggish to start the season. Relax, it’s still September. Come talk to me in December. The Pats could be 0-2 but they aren’t and they’ll be 2-1 after this week. The Falcons are still a young team and they are an indoor team heading outdoors on the road. They don’t play as well on the road as they do at home. Patriots roll, baby.

Pick: Patriots -4

It’s time to hit the sportsbook hardcore as there will be plenty of fighting this weekend. Let’s start with the Mayweather Marquez odds on Saturday.

Boxing odds: Floyd Mayweather vs Juan Manuel Marquez

Pretty Boy Floyd Mayweather is back after a two-year retirement and you know he’s going to get the crowd amped up for this fight. Juan Manuel Marquez is a good fighter and he’s no cupcake, but he’s not Mayweather either. Unless Floyd feels some rust, there is no way that Mayweather loses this fight. Not only is he too fast for Marquez, he’s also too big for him in this contest. Look for Mayweather to beat him up for a while and then knock him out late.

Racebook Picks: Mayweather via 10th Round TKO.

Before we tackle NFL Week 2 betting, let’s not forget about the solid college pigskin this week. This Thursday night, the Miami Hurricanes host Georgia Tech in what could be another barn burner for the Hurricanes.

NCAA football betting: Georgia Tech Yellow Jackets @ Miami Hurricanes

Georgia Tech’s near collapse against Clemson showed us the Yellow Jackets are unpredictable. With Miami, on the other hand, we know what we get. The Hurricanes can score — they dropped 38 points on Florida State and Jacory Harris threw for 386 yards — but they get scored on a ton too. FSU had 404 total yards against them. More importantly, Georgia Tech, who has beaten Miami four straight times, ran for 474 friggin’ yards the last time it faced Miami. Not exactly a recipe for Hurricanes success, is it?

Go with the minor road upset on the strength of Georgia Tech’s running game, which ranks fourth in the nation.

Pick: Georgia Tech +4.5

The NFL Week 1 Matchups are all on the board so let’s get to betting them.

NFL betting: San Diego Chargers @ Oakland Raiders

If you’re into racebook picks, this game should suit you. The horses will be out in this contest as both LaDainian Tomlinson and Darren Sproles are ready to run wild on Oakland. The Raiders gave up 192 rushing yards per game in the preseason and the best part was that they traded for Richard Seymour to improve that running game, but he has yet to report. Tease the Chargers down as they get the job done.

Pick: San Diego -9